Ginkgo Cloud Lab
Overview
Ginkgo Cloud Lab (https://cloud.ginkgo.bio) provides remote access to Ginkgo Bioworks' autonomous lab infrastructure. Protocols are executed on Reconfigurable Automation Carts (RACs) -- modular units with robotic arms, maglev sample transport, and industrial-grade software spanning 70+ instruments.
The platform also includes EstiMate, an AI agent that accepts human-language protocol descriptions and returns feasibility assessments and pricing for custom workflows beyond the listed protocols.
The catalog is organized into Expression & Purification (in vitro / cell-free / E. coli / Pichia), Characterization & Assay, Method & Target Onboarding, and Specialty. Pick a protocol below, then read its reference file for inputs, outputs, the automated workflow, and ordering details.
Available Protocols
Expression & Purification - In vitro
| Protocol |
Readout |
Price |
Turnaround |
Status |
| IVT mRNA/circRNA Synthesis |
qPCR (mRNA or circRNA, 384-well) |
$99/sample |
up to 12 business days |
Certified |
Expression & Purification - Cell-free (E. coli CFPS)
Expression & Purification - E. coli
Expression & Purification - Pichia
| Protocol |
Readout |
Price |
Turnaround |
Status |
| Express + quantify (LabChip) |
Secreted protein, size/purity (up to 96) |
$89/sample |
up to 4 weeks |
Certified (New) |
Characterization & Assay
Method & Target Onboarding
| Protocol |
Readout |
Price |
Turnaround |
Status |
| Onboard Echo-MS method |
Calibration curve, LOD/LOQ |
$799/molecule |
up to 3 weeks |
Certified |
| Onboard SPR target |
Validated SPR capture method |
$1,399/target |
up to 4 weeks |
Beta |
Specialty
Coming soon: Protein Expression and Binding Affinity Characterization (express + purify, then screen binding affinity against a target).
Choosing a Protocol
- Quick expressibility screen? Cell-free HiBiT ($39) or Validate sequence expression ($39).
- Need purified protein + yield? A280 tiers (cell-free or E. coli); add LabChip for purity/size.
- Difficult / membrane / disulfide / cofactor targets? Cell-free Optimize (24-condition DoE).
- Secreted or eukaryotic targets? Pichia expression.
- Screening de novo binders/minibinders? Cell-free or E. coli minibinder tiers, then SPR onboarding for kinetics.
- Enzyme activity / biocatalysis? Echo-MS enzymatic detection (onboard the analyte method first).
- Stability / developability ranking? Thermal shift assay.
- RNA (mRNA/circRNA)? IVT synthesis + qPCR.
General Ordering Workflow
- Select a protocol at https://cloud.ginkgo.bio/protocols
- Configure parameters (number of proteins/samples/molecules/targets, replicates, plates)
- Download the protocol's input template and upload inputs (FASTA/CSV/XLSX for sequence protocols; Design Tool for pixel art; vendor catalog numbers for onboarding)
- Add any special requirements in the Additional Details field
- Provide an email, agree to the protocol terms, and add to cart / submit to receive a feasibility report and price quote
For protocols not listed above, use the EstiMate chat (https://cloud.ginkgo.bio/estimate) to describe a custom protocol in plain language and receive a compatibility assessment and pricing.
Authentication
Access Ginkgo Cloud Lab at https://cloud.ginkgo.bio. Account creation or institutional access may be required. Contact Ginkgo at cloud@ginkgo.bio for access questions.
Key Infrastructure
- RACs (Reconfigurable Automation Carts): Modular robotic units with high-precision arms and maglev transport
- Catalyst Software: Protocol orchestration, scheduling, parameterization, and real-time monitoring
- 70+ integrated instruments: Agilent Bravo liquid handlers, Beckman/Labcyte Echo acoustic dispensers, BMG PHERAstar / Tecan Spark readers, Revvity LabChip, Bio-Rad CFX Opus, Nicoya Alto SPR, SciEx Echo-MS, Inheco/Cytomat incubators, and more
- Nebula: Ginkgo's autonomous lab facility in Boston, MA
